Research has shown that AKG can extend lifespan by up to 50% in roundworms and delay visible signs of aging. This effect may be linked to Ca-AKG’s ability to activate AMP-activated protein kinase (AMPK) – a key cellular pathway that helps maintain energy balance by supporting mitochondrial function and promoting healthy blood sugar regulation. Additionally, studies in aged mice have found that Ca-AKG boosts cellular antioxidant levels, which helped preserve blood vessel elasticity – a key indicator of cardiovascular health.

Research-Supported Benefits:

• Promotes Metabolic Function and Healthy Aging
  Ca-AKG supports metabolic efficiency and longevity by replenishing natural AKG levels that decline with age. It plays a key role in the Krebs cycle, helping convert nutrients into energy and supporting cellular metabolism, which is vital for maintaining vitality over time.
• Stimulates Autophagy for Cellular Renewal
  Autophagy – the body’s internal recycling and repair mechanism, naturally slows down as we age. Ca-AKG has been shown to stimulate this process, helping the body clear out damaged cells and support regeneration at the cellular level.
• Supports Bone and Muscle Strength
  Ca-AKG contributes to protein synthesis and collagen production, both essential for maintaining strong bones and muscle mass. It also fuels ATP production, helping sustain physical performance and structural integrity of the musculoskeletal system.
• Aids in Blood Sugar Regulation
  Age-related decline in insulin sensitivity can lead to unstable blood sugar levels. Research indicates that Ca-AKG may help maintain healthy glucose metabolism, supporting balanced energy levels and metabolic resilience.
• Enhances Cellular and Mitochondrial Health
  By activating AMPK, a key energy-sensing pathway, Ca-AKG supports mitochondrial function and boosts cellular energy production. It also enhances antioxidant defenses, promoting cardiovascular health and protecting cells from age-related oxidative stress.